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Histone H4 (Acetyl-Lys5) Antibody

Histone H4 (Acetyl-Lys5) Antibody

  • 商品品牌:AbSci
  • 商品货号:AB12070
  • 货期: 预计到货1-5
货号 规格 价格
AB12070-1 50ul ¥1450 元
AB12070-2 100ul ¥2250 元
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Primary Antibody
Clonality Polyclonal
Purification Antibodies were produced by immunizing rabbits with synthetic acetylpeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific acetylpeptide. Non-acetyl specific antibodies were removed by chromatogramphy using non-acetylpeptide.
applications WB
Application Details

Predicted MW: 11kd

Western blotting: 1:500~1:1000

Species Reactivity Hu Ms Rt Mk
Specificity The antibody detects endogenous level of Histone H4 only when acetylated at Lysine 5.
Target Name Histone H4
Alternative Names H4, H4/n, H4F2, H4FN, FO108
Accession No. Swiss-Prot#: P62805;
NCBI Gene#: 8359;
NCBI Protein#: NP_003529.1
Modification Acetyl-Lys5
SDS-PAGE MW 11kd
Immunogen Type Peptide-KLH
Immunogen Description Peptide sequence around acetylation site of Lysine 5(S-G-R(p)-G-K) derived from Human Histone H4.
Concentration 1.0mg/ml
Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore Store at -20˚C/1 year
Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Host Species Rabbit

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