您好!欢迎来到Lifesci mall生命科学商城!

客服电话

400-9961-933

当前位置: 首页 > 抗体 > 磷酸化抗体 > p53(Phospho-Ser15) Antibody

最近浏览过的商品

p53(Phospho-Ser15) Antibody

p53(Phospho-Ser15) Antibody

  • 商品品牌:AbSci
  • 商品货号:AB11094
  • 货期: 预计到货1-5
货号 规格 价格
AB11094-1 50ul ¥1450 元
AB11094-2 100ul ¥2250 元
AB11094-4 25ul ¥850 元
购买数量:
  • 商品介绍
  • 商品描述
  • 商品相册
Primary Antibody
Clonality Polyclonal
Purification Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
applications WB IHC IF
Application Details

Predicted MW: 53kd

Western blotting: 1:500~1:1000

Immunohistochemistry: 1:50~1:100

Immunofluorescence: 1:100~1:200

Species Reactivity Hu
Specificity The antibody detects endogenous level of p53 only whenphosphorylated at serine15.
Target Name p53
Alternative Names Tumor suppressor p53; Phosphoprotein p53; Antigen NY-CO-13; TP53;
Accession No. Swiss-Prot: P04637
NCBI Protein: NP_000537.3
Modification Phospho-Ser15
Immunogen Type Peptide-KLH
Immunogen Description Peptide sequence around phosphorylation site of serine 15 (P-L-S(p)-Q-E) derived from Human p53.
Concentration 1.0mg/ml
Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Background

Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.



Lin T, et al. (2005) Nat Cell Biol; 7(2): 165-71.

Vega FM, et al. (2004) Mol Cell Biol; 24(23): 10366-80.

Li J, et al. (2004) J Biol Chem; 279(40): 41275-9.

Wang J, et al. (2004) J Biol Chem; 279(38): 39584-92.

Host Species Rabbit

用户评论

(共0条评论)
  • 暂时还没有任何用户评论
总计 0 个记录,共 1 页。 第一页 上一页 下一页 最末页
用户名: 匿名用户
E-mail:
评价等级:
评论内容:
验证码: captcha
版权所有 2005-2017 南京川博生物技术有限公司(Lifesci mall生命科学商城) All rights reserved
公司地址:江苏省南京市浦口国家高新区星火路10号 电话: 400-9961-933 | E-mail: info@lifescimall.com
增值电信业务经营许可证: 苏B1-20150380 苏ICP备15009006号-2
本商城logo和图片都已申请保护,未经授权不得使用。本商城承诺不会将顾客信息泄漏给任何第三方机构和个人。
有任何购物问题请联系我们在线客服。
  • 电话咨询

  • 400-9961-933