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PCNA Mouse Monoclonal Antibody

PCNA Mouse Monoclonal Antibody

  • 商品品牌:AbSci
  • 商品货号:AB37978
  • 货期: 预计到货1-5
货号 规格 价格
AB37978 100ul ¥1200元
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Primary Antibody
Clonality Monoclonal
Purification Affinity purification using immunogen.
applications WB IHC
Application Details Western blotting: 1:5000
Immunohistochemistry: 1:200
Species Reactivity Hu Ms
Specificity Antibody can detect endogenous?PCNA protein.
Target Name PCNA
SDS-PAGE MW 36kd
Concentration 1.0mg/ml
Formulation Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore Store at -20˚C
Background PCNA is a marker for cells in early G1 phase and S phase of the cell cycle. It is found in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for PCNA. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
Host Species Mouse

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